Diamox helps to reduce the amount of fluid produced as opposed to Lasix which eliminates the fluid already there. I use both. I find I feel better if I take the Diamox in the morning. I am on a low dose so I don't feel the side effects anymore (been on them almost 2 years now). I try to keep pushing the fluids through and the diuretics seem to help keep them flushing through. Main thing is to keep the salt intake very low.